午夜小网站 I 91热热热 I 少妇人妻挤奶水中文视频毛片 I 国精产品99永久一区一区 I 欧美黑人巨大videos极品 I 丰满老女人乱妇dvd在线播放 I 精品一区二区在线看 I 精品亚洲国产成人av I 在线va无卡无码高清 I 亚洲精品大全 I av天天射 I 国产无遮挡无码视频在线观看 I 少妇久久久久久久久久 I 久久精品亚洲精品 I 成人视屏在线 I 午夜色区 I 丁香七月激情 I 亚洲风情av I 97色爽 I 亚洲黄视频在线观看 I 在线播放免费人成毛片乱码 I 青草av久久一区二区三区 I 日本免费视频在线观看 I 久久伊人在 I 成人精品一区二区三区中文字幕 I 2018av天堂在线视频精品观看 I 日韩经典中文字幕 I 亚洲麻豆国产 I 欧洲国产精品无码专区影院 I 一级a毛片高清视频 I 碰超在线97人人 I 看欧美日韩国产 I 小泽玛丽亚在线观看 I 成人在线高清免费 I 精品国产网站

• Anti-Mouse MIF Pre-coated 96 well Strip Microplate
• Mouse MIF Detection Antibody
• Mouse MIF Standard
• Avidin-HRP
• Assay Buffer B
• Wash Buffer (20X)
• Substrate Solution F
• Stop Solution
• Plate Sealers

Macrophage migration inhibitory factor (MIF), also known as glycosylation inhibiting factor (GIF), is a pituitary hormone and a macrophage- and T cell-derived cytokine that plays an important role in the endocrine and immune systems. MIF consists of 115 amino acids and has a molecular weight of 12.5 kD. Mouse MIF shares most of its identity with human (90%), rat (99%), and cattle (88%) MIFs, and a moderate percentage of its identity with MIFs from a wide variety of other species. It exists in monomeric, dimeric, and trimeric forms of identical protomers.

MIF is active as a pro-inflammatory regulator and upregulates multiple cytokines that are vital to combating infections in vivo, including tumor-necrosis factor (TNF), interferon-γ (IFN-γ), and interleukin-12 (IL-12). It is known to maintain cell survival and promote pro-inflammatory immune responses. MIF also activates the ERK1/ERK2 signaling pathway, which inhibits the immunosuppressive effects of glucocorticoids. MIF also plays a critical role in superantigen-induced toxic shock. It upregulates several factors that enhance the growth and invasiveness of gram-negative bacteria. MIF can enhance many inflammatory diseases, such as acute respiratory distress syndrome, arthritis, atopic dermatitis, allograft rejection, glomerulonephritis, inflammatory bowel diseases, asthma, and atherosclerosis. Known receptors for MIF include CXCR2, CXCR4, CD44, and CD74.

The LEGEND MAX™ Mouse MIF ELISA kit is a ready-to-use Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a rat monoclonal anti-mouse MIF antibody. The Detection Antibody is a biotinylated goat polyclonal anti-mouse MIF antibody. This assay is specifically designed to quantify mouse MIF from serum, plasma, cell culture supernatant, and cell lysate. This kit is analytically validated with prepared reagents.